Oral acetyl-L-carnitine therapy and insulin resistance.
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چکیده
منابع مشابه
Oral carnitine therapy and insulin resistance.
Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1000 words (typed double-spaced) in length and may be subject to editing or abridgment. To the Editor: Ruggenenti et al 1 report that oral administration of acetyl-L-carnitine results in a substantial, sustained, and simultaneous improvement in insulin sensitivity and blood pressure in insulin-resista...
متن کاملAmeliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy.
Insulin resistance, a key component of the metabolic syndrome, is a risk factor for diabetes mellitus and cardiovascular disease. Acetyl-L-carnitine infusion acutely ameliorated insulin sensitivity in type 2 diabetics with insulin resistance. In this sequential off-on-off pilot study, we prospectively evaluated the effects of 24-week oral acetyl-L-carnitine (1 g twice daily) therapy on the gluc...
متن کاملتأثیر مکمل یاری L-کارنیتین در مقایسه با تمرین هوازی متوسط بر مقاومت به انسولین و شاخص‌های تن‌سنجی در زنان چاق
Background and Objective: Insulin resistance is one of the key components of metabolic syndrome and a major risk factor for diabetes and cardio-vascular diseases, especially among obese people. The aim of this study was to evaluate the effects of L-carnitine supplementation either with or without moderate aerobic training on insulin resistance and anthropometric indices in obese women. Material...
متن کاملAcetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease.
Mitochondrial abnormalities are suggested to be associated with the development of nonalcoholic fatty liver. Liver mitochondrial content and function have been shown to improve in oral feeding of acetyl-L-carnitine (ALC) to rodents. Carnitine is involved in the transport of acyl-coenzyme A across the mitochondrial membrane to be used in mitochondrial β-oxidation. We hypothesized that oral admin...
متن کاملEditorial Commentary Hypertension and Insulin Resistance
Diminished tissue sensitivity to the metabolic actions of insulin is a characteristic feature of various pathological conditions termed the “cardiometabolic syndrome.”1–3 Factors that contribute to the complex interaction of genetic and environmental factors required for impaired insulin signaling include obesity, inactivity, and aging. Recent research has underscored the importance of heighten...
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عنوان ژورنال:
- Hypertension
دوره 55 6 شماره
صفحات -
تاریخ انتشار 2010